VRTX Options Open Interest by Strike, Oct 21 Settlement
VRTX open interest settled 2026-10-21 vs 2026-10-20.
Source: SquawkFlow's archive of settled open interest. Counts are contracts, not trades; they do not identify which side opened or closed a position.
Computed from the Oct 21 settlement. Next update after the Oct 22 settlement, after 5:30 a.m. PT (8:30 a.m. ET) on Friday, Oct 23, 2026.
All archived unexpired expiration/strike/type keys, including unchanged counts. Series sharing that key are combined; roots and deliverables are not retained. Zero-OI keys omitted by the archive are not reconstructed.
This page shows the 6 nearest of 14 expirations, with the 40 strikes nearest the archived reference price (2026-10-21) for each, plus the largest changes across the whole book. The complete book, 810 expiration/strike/type keys, is in the Markdown table.
Strike bucket on the horizontal axis, settled open contracts per bucket on the vertical axis. Calls in the accent color; puts in orange. Totals across the 6 nearest expirations, strikes from 420 to 629. Source: SquawkFlow's archive of settled open interest. Counts are contracts, not trades; they do not identify which side opened or closed a position.
VRTX: largest changes in the full book, settled 2026-10-21 vs 2026-10-20
Strike
Expiry
Type
Prior OI
Settled OI
Change
500
10/23
put
572
196
-376
520
10/30
call
114
161
+47
512.5
10/23
call
7
51
+44
500
11/27
put
27
61
+34
580
01/15
call
309
333
+24
470
01/15
put
278
297
+19
520
10/23
call
163
178
+15
525
10/23
call
44
59
+15
500
11/20
put
124
113
-11
512.5
11/20
call
2
13
+11
530
11/20
call
69
80
+11
530
10/30
call
167
177
+10
505
11/06
call
5
15
+10
505
11/13
call
0
10
+10
510
11/13
put
55
45
-10
Expiration 2026-10-23
VRTX open interest, settled 2026-10-21, expiration 2026-10-23, strikes 455 to 590
Strike
Expiry
Type
Prior OI
Settled OI
Change
455
10/23
put
5
5
0
460
10/23
put
10
10
0
465
10/23
put
9
9
0
467.5
10/23
put
21
21
0
470
10/23
put
15
15
0
472.5
10/23
put
22
22
0
475
10/23
call
479
479
0
475
10/23
put
73
73
0
477.5
10/23
call
479
479
0
477.5
10/23
put
5
5
0
480
10/23
call
3
3
0
480
10/23
put
28
28
0
482.5
10/23
put
24
24
0
485
10/23
put
19
19
0
487.5
10/23
call
1
1
0
487.5
10/23
put
17
17
0
490
10/23
call
1
1
0
490
10/23
put
37
37
0
492.5
10/23
put
2
2
0
495
10/23
call
5
5
0
495
10/23
put
33
24
-9
497.5
10/23
put
4
5
+1
500
10/23
call
17
17
0
500
10/23
put
572
196
-376
502.5
10/23
call
14
14
0
502.5
10/23
put
5
5
0
505
10/23
call
13
12
-1
505
10/23
put
68
68
0
507.5
10/23
call
10
10
0
507.5
10/23
put
1
2
+1
510
10/23
call
302
303
+1
510
10/23
put
139
139
0
512.5
10/23
call
7
51
+44
512.5
10/23
put
129
130
+1
515
10/23
call
73
73
0
515
10/23
put
246
243
-3
517.5
10/23
call
505
511
+6
520
10/23
call
163
178
+15
520
10/23
put
46
46
0
522.5
10/23
call
63
63
0
525
10/23
call
44
59
+15
525
10/23
put
102
102
0
527.5
10/23
call
96
96
0
527.5
10/23
put
2
2
0
530
10/23
call
220
221
+1
530
10/23
put
20
20
0
535
10/23
call
9
9
0
535
10/23
put
5
5
0
540
10/23
call
23
23
0
545
10/23
call
26
26
0
550
10/23
call
38
38
0
555
10/23
call
49
49
0
560
10/23
call
32
32
0
565
10/23
call
24
24
0
570
10/23
call
27
27
0
575
10/23
call
2
2
0
585
10/23
call
5
5
0
590
10/23
call
6
6
0
Expiration 2026-10-30
VRTX open interest, settled 2026-10-21, expiration 2026-10-30, strikes 440 to 600
Strike
Expiry
Type
Prior OI
Settled OI
Change
440
10/30
put
6
6
0
445
10/30
put
23
23
0
450
10/30
put
4
4
0
455
10/30
put
12
12
0
460
10/30
put
28
28
0
465
10/30
put
46
46
0
470
10/30
call
3
3
0
470
10/30
put
9
9
0
475
10/30
call
3
3
0
475
10/30
put
22
22
0
480
10/30
put
16
16
0
482.5
10/30
put
1
1
0
485
10/30
put
11
11
0
487.5
10/30
put
1
1
0
490
10/30
call
22
22
0
490
10/30
put
4
4
0
492.5
10/30
put
0
1
+1
495
10/30
call
1
1
0
495
10/30
put
61
61
0
497.5
10/30
call
4
4
0
497.5
10/30
put
4
4
0
500
10/30
call
21
21
0
500
10/30
put
528
530
+2
502.5
10/30
call
3
3
0
502.5
10/30
put
1
1
0
505
10/30
call
24
24
0
505
10/30
put
9
9
0
507.5
10/30
call
7
7
0
507.5
10/30
put
2
2
0
510
10/30
call
573
573
0
510
10/30
put
120
120
0
512.5
10/30
call
3
3
0
515
10/30
call
37
37
0
515
10/30
put
41
41
0
517.5
10/30
call
42
43
+1
520
10/30
call
114
161
+47
520
10/30
put
56
56
0
522.5
10/30
call
9
9
0
522.5
10/30
put
0
1
+1
525
10/30
call
32
32
0
525
10/30
put
31
31
0
527.5
10/30
call
25
25
0
530
10/30
call
167
177
+10
530
10/30
put
20
20
0
535
10/30
call
19
28
+9
535
10/30
put
6
6
0
540
10/30
call
30
33
+3
545
10/30
call
25
25
0
550
10/30
call
46
46
0
555
10/30
call
25
25
0
560
10/30
call
23
23
0
570
10/30
call
4
4
0
575
10/30
call
111
111
0
585
10/30
call
1
1
0
595
10/30
call
8
8
0
600
10/30
call
1
1
0
Expiration 2026-11-06
VRTX open interest, settled 2026-10-21, expiration 2026-11-06, strikes 425 to 610
Strike
Expiry
Type
Prior OI
Settled OI
Change
425
11/06
put
2
2
0
430
11/06
put
1
1
0
440
11/06
put
50
50
0
445
11/06
put
3
3
0
450
11/06
put
1
1
0
455
11/06
put
2
2
0
460
11/06
put
7
7
0
465
11/06
call
1
1
0
465
11/06
put
8
6
-2
470
11/06
call
2
2
0
470
11/06
put
3
3
0
475
11/06
put
7
7
0
480
11/06
call
3
1
-2
480
11/06
put
4
4
0
485
11/06
put
6
6
0
490
11/06
call
7
1
-6
490
11/06
put
3
3
0
495
11/06
call
4
4
0
495
11/06
put
2
2
0
497.5
11/06
put
0
1
+1
500
11/06
call
9
9
0
500
11/06
put
52
52
0
505
11/06
call
5
15
+10
505
11/06
put
18
18
0
510
11/06
call
12
12
0
510
11/06
put
12
15
+3
515
11/06
call
9
17
+8
515
11/06
put
35
35
0
520
11/06
call
6
7
+1
520
11/06
put
10
10
0
525
11/06
call
2
2
0
525
11/06
put
28
28
0
530
11/06
call
1
1
0
535
11/06
call
2
5
+3
535
11/06
put
2
2
0
540
11/06
call
8
9
+1
545
11/06
call
3
3
0
550
11/06
call
27
29
+2
555
11/06
call
13
13
0
560
11/06
call
15
15
0
565
11/06
call
3
3
0
575
11/06
call
1
1
0
610
11/06
call
1
1
0
Expiration 2026-11-13
VRTX open interest, settled 2026-10-21, expiration 2026-11-13, strikes 380 to 570
Strike
Expiry
Type
Prior OI
Settled OI
Change
380
11/13
put
2
2
0
400
11/13
put
33
33
0
440
11/13
put
1
1
0
450
11/13
put
7
7
0
455
11/13
put
9
9
0
460
11/13
put
4
4
0
465
11/13
put
1
1
0
470
11/13
put
2
2
0
475
11/13
put
6
6
0
480
11/13
put
8
8
0
485
11/13
put
4
4
0
490
11/13
call
6
0
-6
490
11/13
put
33
33
0
495
11/13
put
31
31
0
500
11/13
call
9
9
0
500
11/13
put
69
69
0
505
11/13
call
0
10
+10
505
11/13
put
16
16
0
510
11/13
call
13
13
0
510
11/13
put
55
45
-10
515
11/13
call
7
12
+5
515
11/13
put
4
6
+2
520
11/13
call
2
2
0
520
11/13
put
6
6
0
525
11/13
call
3
3
0
525
11/13
put
2
2
0
530
11/13
call
28
28
0
535
11/13
call
10
10
0
540
11/13
call
7
7
0
545
11/13
call
41
41
0
550
11/13
call
16
16
0
555
11/13
call
14
14
0
570
11/13
call
1
1
0
Expiration 2026-11-20
VRTX open interest, settled 2026-10-21, expiration 2026-11-20, strikes 380 to 700
Strike
Expiry
Type
Prior OI
Settled OI
Change
380
11/20
put
3
3
0
400
11/20
call
2
3
+1
400
11/20
put
33
33
0
410
11/20
put
31
31
0
430
11/20
put
13
13
0
440
11/20
put
2
2
0
450
11/20
call
1
1
0
450
11/20
put
18
18
0
460
11/20
call
1
1
0
460
11/20
put
69
69
0
470
11/20
put
27
27
0
480
11/20
call
9
9
0
480
11/20
put
73
73
0
490
11/20
call
4
4
0
490
11/20
put
51
49
-2
495
11/20
call
2
2
0
500
11/20
call
30
30
0
500
11/20
put
124
113
-11
505
11/20
call
4
4
0
507.5
11/20
call
330
330
0
510
11/20
call
41
47
+6
510
11/20
put
239
241
+2
512.5
11/20
call
2
13
+11
515
11/20
call
76
83
+7
515
11/20
put
0
6
+6
517.5
11/20
call
1
2
+1
520
11/20
call
33
33
0
520
11/20
put
19
19
0
525
11/20
call
1
2
+1
530
11/20
call
69
80
+11
530
11/20
put
12
13
+1
535
11/20
call
3
3
0
540
11/20
call
337
337
0
550
11/20
call
29
30
+1
555
11/20
call
1
3
+2
560
11/20
call
56
57
+1
570
11/20
call
22
22
0
580
11/20
call
10
10
0
590
11/20
call
3
3
0
600
11/20
call
71
71
0
610
11/20
call
7
7
0
620
11/20
call
72
72
0
650
11/20
call
1
1
0
660
11/20
call
3
3
0
700
11/20
call
1
1
0
Expiration 2026-11-27
VRTX open interest, settled 2026-10-21, expiration 2026-11-27, strikes 340 to 620
Strike
Expiry
Type
Prior OI
Settled OI
Change
340
11/27
put
1
1
0
410
11/27
put
3
3
0
430
11/27
put
1
1
0
440
11/27
put
5
5
0
450
11/27
call
2
2
0
450
11/27
put
2
2
0
460
11/27
put
4
4
0
470
11/27
put
1
2
+1
480
11/27
put
1
1
0
490
11/27
put
5
12
+7
500
11/27
put
27
61
+34
510
11/27
call
21
21
0
510
11/27
put
1
1
0
520
11/27
put
2
2
0
530
11/27
call
10
10
0
530
11/27
put
10
10
0
540
11/27
call
1
6
+5
550
11/27
call
2
2
0
560
11/27
call
0
1
+1
620
11/27
call
1
1
0
Later expirations (2026-12-18, 2027-01-15, 2027-03-19, 2027-04-16, 2027-06-17, 2027-09-17, 2028-01-21, 2029-01-19) and all other strikes are in the Markdown table.